2010. november 30., kedd
Agent 3Z
November29
Commerzbank is a German retail banking company. Their headquarters is located in Frankfurt, Germany.
This is how they pee.
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Three of Favorite iPad Accessory Upgrades | Apartment Therapy Unplggd
Three of Favorite iPad Accessory Upgrades
Unfortunately, the iPurr iPad Stand has yet to go into production, despite strong market demand.
We'd argue the Apple iPad can only get better, more useful, when partnered with one of these accessories that build upon improving portability or the sound of your trusted tablet computer. Here are three we recommend...
SMK Link Paddock 10
Adding some audio kick to your iPad have never been this easier. Plenty of volume with two 3 watts speakers, which can bounce the sound waves off of surfaces behind the stand for better amplification. It can rotate 360 degrees. $99.99
iHome iA100ZC Alarm Clock
This is not another iPad speaker dock. This one can plays MP3s with it built in Bongiovi restorative digital sound technology and wirelessly stream music over Bluetooth. Comes with alarm apps for the iPad and sleep mode that can turn the iPad off after a pre set time. $199
Booq Cobra Courier XS
This bag let your iPad rest on a cushioned, plush compartment while protected all around with ballistic nylon material. Additional space for other peripherals and supplies are plenty. Front access zipper reveals pockets and internal chambers accented with Napa leather trim. $145Main picture from flickr user Veronica Belmont, used under creative commons license.
Untitled
Pu
Egyébként Barnabás hasfájós, de hála egy csodaszernek pár napja gáz nem marad a gyerekben. Egyszerűen hihetetlen, hogy egy ilyen kicsi ember képes a féltenyérnyi fenekével ilyen férfiasakat fingani.
A járókelők a babakocsi mellett elhaladva például nem is hiszik el.
Google Olvasó (1000+)
Kúrásidő
-Kész a kaja. Jössz?
-Dél van. Ebédidő. Megyek.
-Kúrásidő mikor van?:)
-Ebédidő után.:D.....Kúrásidő, ez tetszik.
-Van még süti is kérsz?
-Aha.
-Mivan televagy? Nemkéredmár?
-Nem, nem is akarom már megenni. Cica....áll a farkam de kegyetlenül.
-Mi?:) komolyan? de baszki evés közben? Najó, adda csak ide azt a sütit, visszateszem a hűtőbe.:)
Harvard scientists reverse the ageing process in mice – now for humans | Science | The Guardian
Harvard scientists reverse the ageing process in mice – now for humans
Harvard scientists were surprised that they saw a dramatic reversal, not just a slowing down, of the ageing in mice. Now they believe they might be able to regenerate human organs
- guardian.co.uk, Sunday 28 November 2010 18.01 GMT
- Article history
In mice, reactivating the enzyme telomerase led to the repair of damaged tissues and reversed the signs of ageing. Photograph: Robert F. Bukaty/AP
Scientists claim to be a step closer to reversing the ageing process after rejuvenating worn out organs in elderly mice. The experimental treatment developed by researchers at the Dana-Farber Cancer Institute, Harvard Medical School, turned weak and feeble old mice into healthy animals by regenerating their aged bodies.
The surprise recovery of the animals has raised hopes among scientists that it may be possible to achieve a similar feat in humans – or at least to slow down the ageing process.
An anti-ageing therapy could have a dramatic impact on public health by reducing the burden of age-related health problems, such as dementia, stroke and heart disease, and prolonging the quality of life for an increasingly aged population.
"What we saw in these animals was not a slowing down or stabilisation of the ageing process. We saw a dramatic reversal – and that was unexpected," said Ronald DePinho, who led the study, which was published in the journal Nature.
"This could lead to strategies that enhance the regenerative potential of organs as individuals age and so increase their quality of life. Whether it serves to increase longevity is a question we are not yet in a position to answer."
The ageing process is poorly understood, but scientists know it is caused by many factors. Highly reactive particles called free radicals are made naturally in the body and cause damage to cells, while smoking, ultraviolet light and other environmental factors contribute to ageing.
The Harvard group focused on a process called telomere shortening. Most cells in the body contain 23 pairs of chromosomes, which carry our DNA. At the ends of each chromosome is a protective cap called a telomere. Each time a cell divides, the telomeres are snipped shorter, until eventually they stop working and the cell dies or goes into a suspended state called "senescence". The process is behind much of the wear and tear associated with ageing.
At Harvard, they bred genetically manipulated mice that lacked an enzyme called telomerase that stops telomeres getting shorter. Without the enzyme, the mice aged prematurely and suffered ailments, including a poor sense of smell, smaller brain size, infertility and damaged intestines and spleens. But when DePinho gave the mice injections to reactivate the enzyme, it repaired the damaged tissues and reversed the signs of ageing.
"These were severely aged animals, but after a month of treatment they showed a substantial restoration, including the growth of new neurons in their brains," said DePinho.
Repeating the trick in humans will be more difficult. Mice make telomerase throughout their lives, but the enzyme is switched off in adult humans, an evolutionary compromise that stops cells growing out of control and turning into cancer. Raising levels of telomerase in people might slow the ageing process, but it makes the risk of cancer soar.
DePinho said the treatment might be safe in humans if it were given periodically and only to younger people who do not have tiny clumps of cancer cells already living, unnoticed, in their bodies.
David Kipling, who studies ageing at Cardiff University, said: "The goal for human tissue 'rejuvenation' would be to remove senescent cells, or else compensate for the deleterious effects they have on tissues and organs. Although this is a fascinating study, it must be remembered that mice are not little men, particularly with regard to their telomeres, and it remains unclear whether a similar telomerase reactivation in adult humans would lead to the removal of senescent cells."
Lynne Cox, a biochemist at Oxford University, said the study was "extremely important" and "provides proof of principle that short-term treatment to restore telomerase in adults already showing age-related tissue degeneration can rejuvenate aged tissues and restore physiological function."
DePinho said none of Harvard's mice developed cancer after the treatment. The team is now investigating whether it extends the lifespan of mice or enables them to live healthier lives into old age.
Tom Kirkwood, director of the Institute for Ageing and Health at Newcastle University, said: "The key question is what might this mean for human therapies against age-related diseases? While there is some evidence that telomere erosion contributes to age-associated human pathology, it is surely not the only, or even dominant, cause, as it appears to be in mice engineered to lack telomerase. Furthermore, there is the ever-present anxiety that telomerase reactivation is a hallmark of most human cancers."
Cheating In Exams – How Students Are Cheating | Indian Pakistani Men Magazine
Almost every student out there dream about getting A grade. Some students succeed because of their hard work in studies but lazy and weak students are always looking for shortcuts. They are trying to find methods of cheating in exams. We shouldn’t use any illegal method to pass our exams, because it can destroy our future. So pay you full attention on your studies not at cheating. Anyways we have collected some photographs of students who are using different method of cheating in their exams. 10 Photos
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Power of Earthquake | Travel - Resorts, List, Photo
Back in September there was a powerful earthquake in New Zealand and here are the most unbelievable images of the earthquake aftermath. Let’s see what happened to a railway line during the earthquake and landslide.
» Selbstgemachter Bier-Adventskalender » RawSucker.com
Selbstgemachter Bier-Adventskalender
So macht man einen Bier-Adventskalender selbst.
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